Background and aims: Recent investigations have highlighted the value of neuropsychological testing for the assessment and screening of Alcohol-Related Brain Damage. The aim of the present study was to evaluate the suitability of the Addenbrooke’s Cognitive Examination and the Repeatable Battery for the Assessment of Neuropsychological Status for this purpose. Methods: Comparing 28 participants with ARBD and 30 alcohol-dependent participants without ARBD we calculated Area Under the Curve statistics, sensitivity and specificity values, base-rate adjusted predictive values, and likelihood ratios for (...) both tests. Results: High levels of screening accuracy were found for the total scores of both the ACE-III and RBANS at multiple cut-off points. Removing participants with a history of polysubstance from the samples improved the diagnostic capabilities of the RBANS substantially, while only minor improvements to the ACE-III’s accuracy were observed. Conclusions: Overall, both the ACE-III and RBANS are suitable tools for ARBD screening within an alcohol-dependent population, though the RBANS is the superior of the two. Clinicians using these tools for ARBD screening should be cautious of false-positive outcomes and should therefore combine them with other assessment methods and more detailed neuropsychological testing before reaching diagnostic decisions. (shrink)

Reasoning Towards Utopia In his book, Hesselink measures European Contract Law against the standards of several classical so-called normative political theories. This gives an idea of how European Contract Law fits within a certain intellectual landscape, but there are two things it does not do: it does not tell us how European Contract Law relates to some of the burning issues of the day, and it does not tell us what consequences European Contract Law would actually have. In a time (...) of crisis, should we celebrate the cool cerebral quality of the book’s analysis, or be frustrated that it does not tell us what to do? (shrink)

Recent magnetic resonance imaging and pathological studies have indicated that axonal loss is a major contributor to disease progression in multiple sclerosis. 1 H magnetic resonance spectroscopy, through measurement of N -acetyl aspartate, a neuronal marker, provides a unique tool to investigate this. Patients with primary progressive multiple sclerosis have few lesions on conventional MRI, suggesting that changes in normal appearing white matter, such as axonal loss, may be particularly relevant to disease progression in this group. To test this hypothesis (...) NAWM was studied with MRS, measuring the concentration of N -acetyl derived groups. Single-voxel MRS using a water-suppressed PRESS sequence was carried out in 24 patients with primary progressive multiple sclerosis and in 16 age-matched controls. Ratios of metabolite to creatine concentration were calculated in all subjects, and absolute concentrations were measured in 18 patients and all controls. NA/Cr was significantly lower in NAWM in patients than in controls, as was the absolute concentration of NA. There was no significant difference in the absolute concentration of creatine between the groups. This study supports the hypothesis that axonal loss occurs in NAWM in primary progressive multiple sclerosis and may well be a mechanism for disease progression in this group. (shrink)

As an undergraduate from 1964 to 1967, Gareth Evans, a British philosopher of language and mind, studied for the PPE degree (philosophy, politics and economics) at University College, Oxford, where his philosophy tutor was Peter Strawson. He was then a Senior Scholar at Christ Church, Oxford (1967–68) and a Kennedy Scholar visiting Harvard and Berkeley (1968–69). In 1968, less than a year after completing his degree, Evans was elected to a Fellowship at University College. He took up the position (...) in 1969, succeeding Strawson who had become Waynflete Professor of Metaphysical Philosophy at Oxford. During the 1970s, Evans and his University College colleague John McDowell played leading roles in developing a distinctive conception of truth-theoretic semantics, drawing on the work of Strawson, Michael Dummett, and especially Donald Davidson. Their co-edited collection, Truth and Meaning: Essays in Semantics, appeared in 1976. While philosophy of language enjoyed a central position in Oxford philosophy of that period, Evans did not share the view (regarded by Dummett as constitutive of analytic philosophy) that philosophy of language is foundational and so takes priority over philosophy of mind in the order of philosophical explanation. He attached particular importance to the mentalistic notion of understanding, and his work on the theory of reference was set within a theory of thought and especially thought about particular objects. Evans’s published work ranged over philosophy of language, metaphysics, philosophy of mind, and philosophy of psychology. In 1979 he was elected to the Wilde Readership in Mental Philosophy at Oxford. He died in August 1980, at the age of thirtyfour. His book, The Varieties of Reference (1982), incomplete at the time of his death, was edited and brought to publication by McDowell. A collection of thirteen of his papers and two shorter notes appeared in 1985 and a further note was published in 2004.. (shrink)

I review and reconsider some of the themes of ‘Two notions of necessity’ (Davies and Humberstone, 1980) and attempt to reach a deeper understanding and appreciation of Gareth Evans’s reflections (in ‘Reference and contingency’, 1979) on both modality and reference. My aim is to plot the relationships between the notions of necessity that Humberstone and I characterised in terms of operators in two-dimensional modal logic, the notions of superficial and deep necessity that Evans himself described, and the epistemic (...) notion of a priority. (shrink)

In his paper ‘Scmantic Theory and Tacit Knowlcdgc’, Gareth Evans uscs a familiar kind of cxamplc in ordcr to render vivid his account of tacit knowledge. We arc to consider a finite language, with just one hundrcd scntcnccs. Each scntcncc is made up of a subjcct (a name) and a prcdicatc. The names are ‘a’, ‘b’, . . ., T. The prcdicatcs arc ‘F’, ‘G’, . . ., ‘O’. Thc scntcnccs have meanings which dcpcnd in a systematic way upon (...) their construction. Thus, all scntcnccs containing ‘a’ mean something about john; all scntcnccs containing ‘b’ mean something about Harry; all scntcnccs containing ‘F’ mean something about being bald; all scntcnccs containing ‘G’ mean something about being happy; and so 011. For this vcry simple language L, wc arc to consider various semantic theories. We could consider thcorics whosc dclivcranccs about wholc scntcnccs are of.. (shrink)

The great Roman historian Livy describes a radical attempt at conflict resolution in his version of the story of the Horatii. The warring cities of Rome and Alba agree to settle their differences by pitting two sets of triplets against each other in a battle to the death. Two of the Roman champions, the Horatii, are killed, but the remaining brother wins the day for his city. In a further twist, he then goes on to kill his sister when he (...) finds her grieving for one of the dead Alban brothers, to whom she was betrothed. Although guilty of a dreadful crime, by the will of the people the murderer is spared because of his services to the state. In the version of the story dramatized by the seventeenth-century French playwright Pierre Corneille, it is rather the Roman king who saves the surviving Horatius by deeming that his heroism places him above the law. This article considers whether the interests of the state can offset private crimes, as appears to be the case in the versions of the story told by both Livy and Corneille; and it concludes by referring to Livy's continuation of the story, which shows the resolution of the conflict to be short-lived. (shrink)

This article explores Gareth Evans’s idea that there are such things as descriptive names, i.e. referring expressions introduced by a definite description which have, unlike ordinary names, a descriptive content. Several ignored semantic and modal aspects of this idea are spelled out, including a hitherto little explored notion of rigidity, super-rigidity. The claim that descriptive names are (rigidified) descriptions, or abbreviations thereof, is rejected. It is then shown that Evans’s theory leads to certain puzzles concerning the referential status of (...) descriptive names and the evaluation of identity statements containing them. A tentative solution to these puzzles is suggested, which centres on the treatment of definite descriptions as referring expressions. (shrink)

Stephen Davies presents a fascinating exploration of the idea that art, and our aesthetic sensibilities more generally, should be understood as an element in human evolution. He asks: Do animals have aesthetics? Do our aesthetic preferences have prehistoric roots? Is art universal? What is the biological role of aesthetic and artistic behaviour?

In this richly argued and provocative book, David Davies elaborates and defends a broad conceptual framework for thinking about the arts that reveals important continuities and discontinuities between traditional and modern art, and between different artistic disciplines. Elaborates and defends a broad conceptual framework for thinking about the arts. Offers a provocative view about the kinds of things that artworks are and how they are to be understood. Reveals important continuities and discontinuities between traditional and modern art. Highlights core (...) topics in aesthetics and art theory, including traditional theories about the nature of art, aesthetic appreciation, artistic intentions, performance, and artistic meaning. (shrink)

Many assume that theories of distributive justice must obviously take people’s lifetimes, and only their lifetimes, as the relevant period across which we distribute. Although the question of the temporal subject has risen in prominence, it is still relatively underdeveloped, particularly in the sphere of health and healthcare. This paper defends a particular view, “momentary sufficientarianism,” as being an important element of healthcare justice. At the heart of the argument is a commitment to pluralism about justice, where theorizing about just (...) principles demands paying attention to the role particular goods play in our lives. This means that different approaches to the temporal subject—as well as other relevant issues—may be appropriate for different goods, including different goods within healthcare. In particular, the paper discusses two central goods targeted by healthcare: life-saving and pain relief. The view is offered as complementary to, rather than competitive with, lifetime approaches. As such, the paper finishes by considering how a pluralist approach, which engages both with people’s lives as a whole and with their states at particular moments, can reconcile the potentially competing claims in healthcare that emerge from these two perspectives. (shrink)

Thinking is special. There is nothing quite like it. Thinking.

A good deal of moral criticism employed in everyday life associates, in a variety of ways and in varying degrees of complexity, selfish behaviour and attitudes with a deficiency in what Dr Leavis calls ‘ethical sensibility’. A primitive ethical sensibility is a species of ignorance; it is to be unperceptive, muddled, superficial, undiscriminating and slipshod in one's understanding and appreciation of the nature and quality of one's own and other people's experience. It might involve, for example, being afflicted with sentimentalism; (...) perceiving people through a distorting medium of stereotypes or impressionistically; being dominated by wishful thinking in the Freudian sense; holding beliefs on the basis of hearsay, authority, or because it suits one to hold them; being immersed in situations and relationships whose continued existence requires self-deception; having the sense of one's own worth be wholly dependent upon the opinions of others. A developed ethical sensibility, on the other hand, includes what Professor Peters and others believe to be among the defining characteristics of rationality—impartiality; a caring for clarity, evidence, relevance, consistency and sincerity; a willingness to question authorities, tradition and one's own motives; refusing to be tempted by the cosiness of easy certainties and the stock response. The content of such a sensibility will, of course, depend upon the context in which reason is employed, and attempts to describe the content must take the form of a detailed discussion of particular cases. (shrink)

This is not a random collection of essays, but a book on a single theme. Written by separate hands, mainly by literary critics at Cambridge, it was planned as a whole and executed with a common purpose: to produce the first literary study of the English moralists of the seventeenth century to the beginning of the twentieth. The authors share two convictions: they believe that the study of literature demands an understanding of whatever moral philosophy is embodied in it; and (...) they believe that philosophical writings are capable of being tested by the techniques of literary criticism. In this book, such works as Bacon's Advancement of Learning, Hobbes's Leviathan, and Hume's Enquiries are viewed as whole works, not as repositories of philosophical propositions, nor as episodes in the history of English thought. (shrink)

Priorities in Medical Research was published in 1988 by a select committee of the House of Lords. The report ushered in an era of NHS research and development that lasted from 2001 to 2006. The inquiry's origins lay in concerns about academic medicine in the United Kingdom, yet PMR gave relatively little attention to this subject. Instead the report focused critically on the disconnect between the Department of Health and the NHS in R & D. This, the committee argued, had (...) led to the neglect of research into health services and public health. To sidestep the report's unwelcome proposal for a National Health Research Agency, the department eventually grafted R & D management onto structures created as part of wider NHS reforms. The Medical Research Council successfully pursued a strategy of keeping the committee's attention away from sensitive aspects of its own programme. The final focus of PMR was shaped by an alignment between committee members with an industrial view of research and champions of health services research. The actions of the various actors involved are interpreted using elite models of the state, and the applicability of these models is critically examined. (shrink)

I defend the non-cognitivist outlook on knowledge of grammar from the criticisms levelled against it by Jonathan Knowles. The first part of the paper is largely critical. First, I argue that Knowles's argument against Christopher Peacocke and Martin Davies's non-cognitivist account of the psychological reality of grammar fails, and thus that no reason has been given to think that cognitivism is integral to an understanding of Chomskyan theoretical linguistics. Second, I argue that cognitivism is philosophically problematic. In particular, I (...) argue (a) that Knowles misunderstands Stephen Stich and Gareth Evans's points about inferential integration; and (b) that Knowles misunderstands the philosophical status and demands of Evans's Generality Constraint. In the final, non-critical part of the paper, I try to show that the Stich and Evans's constraints, together with a Self-Knowledge Constraint, are genuine constitutive constraints by showing how they have rationality as their underlying organizing principle. I argue further that recognizing the constitutive character of these constraints allows one to distinguish two kinds of psychological explanation; in this sense, the constraints mark a genuine boundary in our theorizing about the mind. (shrink)

It is often thought that traditional recidivism prediction tools used in criminal sentencing, though biased in many ways, can straightforwardly avoid one particularly pernicious type of bias: direct racial discrimination. They can avoid this by excluding race from the list of variables employed to predict recidivism. A similar approach could be taken to the design of newer, machine learning-based (ML) tools for predicting recidivism: information about race could be withheld from the ML tool during its training phase, ensuring that the (...) resulting predictive model does not use race as an explicit predictor. However, if race is correlated with measured recidivism in the training data, the ML tool may ‘learn’ a perfect proxy for race. If such a proxy is found, the exclusion of race would do nothing to weaken the correlation between risk (mis)classifications and race. Is this a problem? We argue that, on some explanations of the wrongness of discrimination, it is. On these explanations, the use of an ML tool that perfectly proxies race would (likely) be more wrong than the use of a traditional tool that imperfectly proxies race. Indeed, on some views, use of a perfect proxy for race is plausibly as wrong as explicit racial profiling. We end by drawing out four implications of our arguments. (shrink)

The Genre Legong is a secular (balih-balihan) Balinese dance genre (Anon. 1971).[1] Though originally associated with the palace,[2] legong has long been performed in villages, especially at temple ceremonies, as well as at Balinese festivals of the arts. Since the 1920s, abridged versions of legong dances have featured in concerts organized for tourists and in overseas tours by Balinese orchestras. Indeed, the dance has become culturally emblematic, and its image is used to advertise Bali to the world. Traditionally, the dancers (...) are three young girls; the servant (condong), who dances a prelude, and two legong. All wear elaborate costumes of gilded cloth with ornate accessories and frangipani-crowned headdresses.[3] The core repertoire consists of about fifteen dances (some of which are now lost), ranging in their longest versions from thirty to sixty minutes. Some of these are narrative, while others are abstract or general representations of nature, birds, insects, or plants. Those that involve narratives are, nevertheless, highly stylized, and the presentation of the drama is always secondary to the beauty of the dance. The genre is regarded as a treasury of the movements for Balinese women’s dance, and no dancer’s training is complete if she lacks a solid grounding in legong. The dance is accompanied by a gamelan of twenty-five or more players.[4] Though the legong dance remains popular in areas of traditional strength, and despite efforts to revive it, it is generally in decline (Davies 2006). (shrink)

In his 2014 book Fiction and Narrative, Derek Matravers mounts a concerted attack on what he terms the ‘post-Walton consensus’ as to the features that distingui.

Two-dimensional semantics is a framework that helps us better understand some of the most fundamental issues in philosophy: those having to do with the relationship between the meaning of words, the way the world is, and our knowledge of the meaning of words. This selection of new essays by some of the world's leading authorities in this field sheds fresh light both on foundational issues regarding two-dimensional semantics and on its specific applications. Contributors: Richard Breheny, Alex Byrne, David Chalmers, Martin (...) Davies, Gareth Evans, Manuel Garcia-Carpintero, Josep Maci`, Martine Nida-Rumelin, Christopher Peacocke, James Pryor, Francois Recanati, Scott Soames, Cara Spencer, Robert Stalnaker, Kai-Yee Wong, Stephen Yablo. (shrink)

Training for members of research ethics committees varies from state to state in Europe. To follow this up, the European Forum for Good Clinical Practice organised a workshop in March 2007 to explore these issues and look for solutions. This article summarises the discussion, providing ways forward to develop REC training.

Being human while trying to scientifically study human nature confronts us with our most vexing problem. Efforts to explicate the human mind are thwarted by our cultural biases and entrenched infirmities; our first-person experiences as practical agents convince us that we have capacities beyond the reach of scientific explanation. What we need to move forward in our understanding of human agency, Paul Sheldon Davies argues, is a reform in the way we study ourselves and a long overdue break with (...) traditional humanist thinking. Davies locates a model for change in the rhetorical strategies employed by Charles Darwin in _On the Origin of Species_. Darwin worked hard to anticipate and diminish the anxieties and biases that his radically historical view of life was bound to provoke. Likewise, Davies draws from the history of science and contemporary psychology and neuroscience to build a framework for the study of human agency that identifies and diminishes outdated and limiting biases. The result is a heady, philosophically wide-ranging argument in favor of recognizing that humans are, like everything else, subjects of the natural world—an acknowledgement that may free us to see the world the way it actually is. (shrink)

What is critical thinking, especially in the context of higher education? How have research and scholarship on the matter developed over recent past decades? What is the current state of the art here? How might the potential of critical thinking be enhanced? What kinds of teaching are necessary in order to realize that potential? And just why is this topic important now? These are the key questions motivating this volume. We hesitate to use terms such as “comprehensive” or “complete” or (...) “definitive,” but we believe that, taken in the round, the chapters in this volume together offer a fair insight into the contemporary understandings of higher education worldwide. We also believe that this volume is much needed, and we shall try to justify that claim in this introduction. (shrink)

post hos elefantorum fulgentium formidandam speciem et truculentos hiatus uix mentes pauidae perferebant; ad quorum stridorem odoremque et insuetum aspectum magis equi terrebantur. COKNELISSEN, Mnemosyne, xiv , 280, comments: ‘Non intellego fulgentium. Minime audiendus est Wagnerus, qui fulgentes elephantes dictos esse contendit ob cutem glabram. Corrigendum puto ingentium. Porro non satis intellego quomodo hiatus elefantorum militibus pauorem incutere potuerit. Wagnerus, qui omnia con-coquere solet, interpretatur proboscidas. Nescio an scripserit A. barritus.’.

The honour of being the first to teach philosophy in Australia belongs to the Congregationalist minister Barzillai Quaife (1798–1873), in the 1850s, but teaching philosophy did not formally begin until the 1880s, with the establishment of universities (Grave 1984). -/- Two approaches have dominated Western philosophy in Australia: Idealism and materialism. Idealism was prevalent between the 1880s and the 1930s, but dissipated thereafter. It was particularly associated with the work of the first professional philosophers in Australia, such as Henry Laurie (...) (1837–1922), Francis Anderson (1858–1941), William Mitchell (1861–1962) (who rejected the label) and a second generation including W. R. Boyce Gibson (1869–1935). Idealism in Australia often reflected Kantian themes, together with the British, particularly Scottish, revival of interest in Hegel through the work of the ‘Absolute Idealists’ T. H. Green (1836–1882), F. H. Bradley (1846–1924) and Henry Jones (1852–1922), the latter of whom conducted a popular lecture tour of Australia (Boucher 1990). -/- A number of the early New Zealand philosophers, including Duncan MacGregor (1843–1906), William Salmond (1835–1917), and Francis W. Dunlop (1874–1932) were educated in the Idealist tradition and were influential in their communities, but produced relatively little. William Anderson (1889–1955), at Auckland, brother of John at Sydney, was the only New Zealand philosopher that seemed to retain Idealist views. -/- In Australia, materialism gained prominence through the work of John Anderson, who arrived in Australia in 1927, and continues to be influential. John Anderson had been a student of Henry Jones, who can be said to have influenced both strands of Australian philosophical thought. (shrink)

This article explores the development of a novel biomedical research organism, and its potential to remake the species and spaces of translational medicine. The humanized mouse is a complex experimental object in which mice, rendered immunodeficient through genetic alteration, are engrafted with human stem cells in the hope of reconstituting a human immune system for biomedical research and drug testing. These chimeric organisms have yet to garner the same commentary from social scientists as other human–animal hybrid forms. Yet, they are (...) rapidly being positioned as central to translational medicine in immunological research and pharmaceutical development. This article explores the complex relations between species and spaces they seek to enact. Humanizing mice simultaneously moves these animal forms towards the intimate geographies of corporeal equivalence with humans and the expansive geographies of translational research. These multiple trajectories are achieved by the way humanized mice function as both uncertain ‘epistemic things’ and as expansive ‘collaborative things’, articulating mouse genetics with other research, notably stem cell science. In the context of post-genomics, their indeterminacy is critical to their collaborative value; their expansive potential follows as much from their biological openness as from specific expectations. Yet, these new research organisms have both accumulative and disruptive capacities, for there are patterns of interference between these trajectories, remaking boundaries between experimental practices and clinical contexts. (shrink)

Kant distinguishes between ‘active’ and ‘passive’ citizens and holds that only the former are civilly self-sufficient and possess rights of political participation. Such rights are important, since for Kant state institutions are a necessary condition for individual freedom. Thus, only active citizens are entitled to contribute to a necessary condition for the freedom of each. I argue that Kant attributes civil self-sufficiency to those who are not under the authority of any private individual for their survival. This reading is more (...) textually grounded than the dominant reading, which understands civil self-sufficiency in terms of economic relations alone. I further argue that Kant was interested in relations of authority because he was concerned to eliminate certain forms of corruption. This indicates that Kant’s contested distinction between active and passive citizens was a response to a key problem of any account of public lawgiving. (shrink)